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首页> 外文期刊>Journal of vascular surgery >Endovascular repair of ruptured thoracic aortic aneurysms is associated with high perioperative mortality and morbidity.
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Endovascular repair of ruptured thoracic aortic aneurysms is associated with high perioperative mortality and morbidity.

机译:胸主动脉瘤破裂的血管内修复与围手术期高死亡率和高发病率有关。

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摘要

PURPOSE: To analyze early and midterm results after endovascular treatment of ruptured thoracic aortic aneurysms (rTAA). METHODS: Between January 1997 and January 2009, a total of 236 patients received thoracic aortic repair in our institution; 23 patients (14 men; median age, 75 years; range, 60-88 years) due to a ruptured thoracic aortic aneurysm (rTAA). Rupture was defined according to computed tomography angiography (CTA) criteria with definite sign for hemorrhage outside the aortic wall. Patients with symptomatic TAA but with normal CT scans were excluded. A retrospective analysis of these patients was performed. Median follow up was 28 months (range, 0.1-82.5 months) and included serial aortic imaging at discharge, six, and 12 months and annually thereafter. RESULTS: Technical success rate was 87%. The overall in hospital mortality was 48% with predominantly (50%) cardiac complications. Neurological complications occurred in three patients, two patients suffered from a transient ischemic attack (TIA)/stroke, and one patient experienced paraplegia after early conversion to open surgery. Primary endoleaks were seen in four of 25 patients (16%); no secondary endoleak was observed. Early conversion was necessary in two patients caused by an aortoesophageal fistula. The one- and three-year survival rates were 37.3% and 29.9% with no aortic or procedure-related death during follow up. Reintervention was necessary in four of 25 patients (16%). Cox regression analysis revealed preoperative renal insufficiency (hazard ratio [HR] 5.85, P = .0073) as an independent predictor of perioperative death. CONCLUSIONS: The endovascular treatment of ruptured thoracic aortic aneurysms is associated with a high perioperative mortality and morbidity as well as poor midterm survival. Renal insufficiency proved to be an independent risk factor for perioperative death.
机译:目的:分析胸腔主动脉瘤破裂(rTAA)的腔内治疗后的早期和中期结果。方法:1997年1月至2009年1月,在我们机构中共有236例患者接受了胸主动脉修复。因胸主动脉瘤破裂(rTAA)导致的23例患者(14名男性;中位年龄为75岁;范围为60-88岁)。根据计算机断层造影血管造影(CTA)标准定义破裂,主动脉壁外有明确的出血迹象。有症状的TAA但CT扫描正常的患者被排除在外。对这些患者进行了回顾性分析。中位随访时间为28个月(范围0.1-82.5个月),包括出院时的连续主动脉成像,6和12个月,此后每年。结果:技术成功率为87%。总体医院死亡率为48%,主要是(50%)心脏并发症。 3例患者发生神经系统并发症,2例患有短暂性脑缺血发作(TIA)/中风,1例患者在早期改用开放手术后出现了截瘫。 25例患者中有4例(16%)出现原发性内漏;没有观察到次级内渗。对于两名由主动脉食管瘘引起的患者,必须尽早进行转换。随访期间的一年和三年生存率分别为37.3%和29.9%,无主动脉或与手术相关的死亡。 25名患者中有4名(16%)需要再次干预。 Cox回归分析显示术前肾功能不全(危险比[HR] 5.85,P = .0073)是围手术期死亡的独立预测指标。结论:胸腔主动脉瘤破裂的血管内治疗与围手术期高死亡率和高发病率以及中期生存期差有关。肾功能不全被证明是围手术期死亡的独立危险因素。

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