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Independence and mobility after infrainguinal lower limb bypass surgery for critical limb ischemia

机译:下肢旁路手术治疗严重肢体缺血后的独立性和活动性

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Background Critical limb ischemia (CLI) is a common condition associated with high levels of morbidity and mortality. Most work to date has focused on surgeon-oriented outcomes such as patency, but there is increasing interest in patient-oriented outcomes such as mobility and independence. Objective This study was conducted to determine the effect of infrainguinal lower limb bypass surgery (LLBS) on postoperative mobility in a United Kingdom tertiary vascular surgery unit and to investigate causes and consequences of poor postoperative mobility. Methods We collected data on all patients undergoing LLBS for CLI at our institution during a 3-year period and analyzed potential factors that correlated with poor postoperative mobility. Results During the study period, 93 index LLBS procedures were performed for patients with CLI. Median length of stay was 11 days (interquartile range, 11 days). The 12-month rates of graft patency, major amputation, and mortality were 75%, 9%, and 6%, respectively. Rates of dependence increased fourfold during the first postoperative year, from 5% preoperatively to 21% at 12 months. Predictors of poor postoperative mobility were female sex (P =.04) and poor postoperative mobility (P <.001), initially and at the 12-month follow-up. Patients with poor postoperative mobility had significantly prolonged hospital length of stay (15 vs 8 days; P <.001). Conclusions Patients undergoing LLBS for CLI suffer significantly impaired postoperative mobility, and this is associated with prolonged hospital stay, irrespective of successful revascularization. Further work is needed to better predict patients who will benefit from revascularization and in whom a nonoperative strategy is optimal.
机译:背景严重肢体缺血(CLI)是与高发病率和高死亡率相关的常见疾病。迄今为止,大多数工作都集中在以外科医师为导向的结局(例如通畅)上,但人们对以患者为导向的结局(例如活动性和独立性)的兴趣日益增加。目的本研究旨在确定英国三级血管外科单位的下尿道下肢旁路手术(LLBS)对术后活动性的影响,并调查术后活动性差的原因和后果。方法我们收集了在我们机构中为期3年的所有接受LLBS进行CLI的患者的数据,并分析了与术后行动不便相关的潜在因素。结果在研究期间,对CLI患者进行了93次索引LLBS程序。中位住院时间为11天(四分位间距为11天)。十二个月的移植物通畅率,大截肢率和死亡率分别为75%,9%和6%。术后第一年的依赖率增加了四倍,从术前的5%增加到12个月的21%。术后初期和术后12个月,术后活动能力差的预测指标为女性(P = .04)和术后活动能力差(P <.001)。术后行动不便的患者住院时间明显延长(15 vs 8天; P <.001)。结论接受CLI的LLBS的患者术后活动能力明显受损,这与住院时间延长无关,无论是否成功进行血运重建。需要做进一步的工作来更好地预测将受益于血运重建并且最佳手术方法的患者。

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