Increased humoral antibody response of foot-and-mouth disease virus vaccine in growing pigs pre-treated with poly-gamma-glutamic acid

摘要

This study was conducted to determine if humoral antibody response of foot-and-mouth disease (FMD) vaccine improved in 8-week-old growing pigs born to well-vaccinated sows pre-treated with 60 mg of poly-gamma-glutamic acid (gamma-PGA) three days before vaccination. Antibody against FMD virus serotype 0 was measured 0, 2, 4 and 6 weeks post-vaccination, using a PrioCHECK FMDV type 0 ELISA kit. The results showed that positive antibody reactions against FMDV serotype 0 antigen among a component of the vaccine significantly increased in response to pre-injection with gamma-PGA.