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Immunological intervention for the control of ectoparasites of livestock -- a review

机译:免疫干预控制家畜体外寄生虫-综述

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摘要

The majority of parasites affecting a herd of animals are harboured by a relatively few very susceptible hosts within the herd. Those few animals are responsible for the maintenance and transmission of the parasite population to the more resistant animals. This observation has long held the promise of ectoparasite control by natural host resistance if the resistant phenotype could be selected for, or the susceptible phenotype converted to a more resistant status by vaccination. The purpose of thisreview is to direct readers to the literature available on the subject, attempt to summarize recent advances in the field, and outline advancing technologies that hold promise for the identification of resistant and susceptible genotypes, and the manipulation of host innate and acquired immunological resistance mechanisms for safe, sustainable control of arthropod pests of livestock.
机译:影响畜群的大多数寄生虫被畜群内相对少数非常易感的宿主所庇护。那几只动物负责将寄生虫种群维持和传播给更具抵抗力的动物。如果可以选择抗性表型,或者通过疫苗接种将易感表型转化为更强的抗性表型,则该观察长期以来有望通过自然宿主抗性控制外寄生虫。这篇综述的目的是引导读者阅读有关该主题的文献,试图总结该领域的最新进展,并概述一些有前途的技术,这些技术有望用于鉴定抗药性和易感基因型,以及对宿主先天性和后天免疫性疾病的处理。安全,可持续控制牲畜节肢动物害虫的抗药性机制。

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