Parametric study of a variable-magnetic-field-based energy-selection system for generating a spread-out Bragg peak with a laser-accelerated proton beam

摘要

Laser-based proton beam acceleration, which produces broad energy spectra, is unsuitable for direct clinical use. Thus, employing an energy selection system is necessary. The purpose of the present study was to investigate a method whereby a variable magnetic field could be employed with an energy selection system to generate a spread-out Bragg peak (SOBP). For energy selection, particle transport and dosimetric property measurements, the Geant4 toolkit was implemented. The energy spectrum of the laser-accelerated proton beam was acquired using a particle-in-cell simulation. The hole size and the position of the energy selection collimator were varied in order to determine the effects of those parameters on the dosimetric properties. To generate an SOBP, we changed the magnetic field in the energy selection system for each beam weighting factor during beam irradiation. The overall results of this study suggest that the use of an energy selection system with a variable magnetic field can effectively generate an SOBP suitable for proton radiation therapy applications.