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首页> 外文期刊>Clinical neurophysiology >Hand cortical representation at rest and during activation: gender and age effects in the two hemispheres.
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Hand cortical representation at rest and during activation: gender and age effects in the two hemispheres.

机译:静止和激活期间的手部皮质表示:两个半球的性别和年龄影响。

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OBJECTIVE: To characterize the age- and gender- dependence of sensory hand cortical representation in the two hemispheres in healthy population. METHODS: In 57 adults, the cerebral activity from rolandic areas as detected by magnetoencephalography was considered both in a resting state (spectral power properties) and in response to the electrical stimulation of the contralateral median nerve (M20 and M30 cortical sources). RESULTS: We found a dependence of rest and evoked activity on age (alpha rhythm slowing, high frequency power increase, M20 latency increase, M20 strength increase, no change in M30) and on gender (higher alpha frequency, higher beta power, higher spectral entropy, lower M20 amplitude in women). These changes were quite symmetrical in the two hemispheres, making the interhemispheric differences non-dependent on age and gender. Moreover, lower total power and faster alpha rhythm appeared in the dominant hemisphere. CONCLUSIONS: Age and gender have a significant effect on spontaneous and evoked activity at the primary sensorimotor cortex. SIGNIFICANCE: The results consolidate the reference base in healthy population, to study pathological conditions. Inter-hemispheric asymmetries are confirmed as a sensitive indicator for the early identification of possible neuronal rearrangements due to unilateral brain injuries.
机译:目的:表征健康人群中两个半球的感觉手皮层表征的年龄和性别依赖性。方法:在57名成年人中,通过脑磁图检查发现,在静止状态(频谱功率特性)和对侧正中神经的电刺激(M20和M30皮质源)响应时,通过脑磁图检查发现的来自罗兰迪地区的大脑活动。结果:我们发现休息和诱发的活动对年龄(阿尔法节律减慢,高频能量增加,M20潜伏期增加,M20强度增加,M30没有变化)和性别(较高的阿尔法频率,较高的β能量,较高的频谱)有依赖性熵,降低女性的M20幅度)。这些变化在两个半球中非常对称,从而使半球之间的差异与年龄和性别无关。此外,较低的总功率和较快的alpha节奏出现在占优势的半球中。结论:年龄和性别对原发性感觉运动皮层的自发和诱发活动有显着影响。意义:该结果巩固了健康人群的参考基础,以研究病理状况。半球间不对称被确认为早期识别单侧脑损伤可能引起的神经元重排的敏感指标。

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