Solubility Measurements of Surfactants and Dissolution of Cytochrome c in 1,1,1,2-Tetrafluoroethane Modified with Organic Solvents

摘要

The solubilities of four surfactants,sodium bis-2-ethylhexyl sulfosuccinate (AOT),cetyltrimethyl-ammonium chloride,didodecyldimethylammonium bromide,and n-dodecyltrimethylammonium chloride in liquid refrigerant 1,1,1,2-tetrafluoroethane (R134a) modified with methanol,ethanol,and 2-pro-panol were measured.The measurements were performed under 25 and 50 bar at 25 °C.The solubility of AOT was as high as 92 mM in R134a with addition of 2% ethanol.Cytochrome c molecules were then verified to be soluble in the AOT-containing and ethanol-modified R134a solution.Accordingly,liquid R134a is suggested as a potential extraction solvent for hydrophilic compounds.