Erratum: Effects of macromolecular crowding on an intrinsically disordered protein characterized by small-angle neutron scattering with contrast matching (Biophysical Journal (2013) 100: 4 (1120-1128))

摘要

Fig. 4 of the original paper showed the results of a computational simulation of crowding effects on a disordered protein, the N protein of bacteriophage , and Fig. 5 showed the results of fitting experimental small-angle neutron scattering (SANS) data to those predicted by the simulations. Upon reexamining the computational data, the authors have discovered an error in a computer program used in the simulations. This error led to a significant overestimate of the radius of the equivalent sphere used to represent the excluded volumes of the disordered protein molecules and, in turn, an overestimate of the predicted changes in the distribution of conformations making up the disordered ensemble. The corrected figures are shown here.