Strip patch test vs. conventional patch test to detect type IV sensitization in patients with allergic contact dermatitis

摘要

Spier and Natzel first mentioned the strip patch test (SPT) as a modification of the patch test (PT) in their works about chromate allergy. The fundamental idea of the SPT was to obtain more reliable and sensitive patch test results by increasing the bioavailability of test substances in the deeper epidermal cell layers. This was achieved by stripping the test site several times with an adhesive tape prior to the application of the test substances. To date, the SPT is used in diagnostic routine (e.g. for testing substances with a poor percutaneous penetration or for clarifying a contact allergy in case of a negative PT). However, in contrast to the PT, no standardized recommendation for the SPT exists.