Synthesis of Some Novel Hydrazone Derivatives as Antifungal Agents

摘要

A series of novel 2-(substituted-2-benzylidenehydrazinyl)-3-chloropyridine derivatives were designed and synthesized from 2,3-dichloropyridine as starting materials, and their structures were confirmed by H-1 NMR, MS and elemental analysis. The antifungal activity of title compounds was determined. The antifungal assay showed that some of title compounds displayed excellent activity, especially against Stemphylium lycopersici (Enjoji) Yamamoto and Fusarium oxysporum. sp. cucumebrium.