首页> 外文期刊>Journal of the Chemical Society of Pakistan >Synthesis, Crystal Structure and Biological activity of N-(5-(o-tolyl)-l, 3,4-thiadiazol-2-yl)cyclopropanecarboxamide
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Synthesis, Crystal Structure and Biological activity of N-(5-(o-tolyl)-l, 3,4-thiadiazol-2-yl)cyclopropanecarboxamide

机译:N-(5-(邻甲苯基)-1,3,4-噻二唑-2-基)环丙烷甲酰胺的合成,晶体结构和生物活性

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摘要

A new 1, 3, 4-thiadiazole compound, JV-(5-(o-tolyl)-l,3,4-thiadiazol-2-yl) cyclopropanecarboxamide, was synthesized and its structure was confirmed by ~1H NMR, MS and HRMS. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test showed that the synthesized compound has moderate herbicidal activity against Brassica campestris and fungicidal activities against Sclerotinia sclerotiorum(Lib.) de Bary, Rhizoctonia solanii, Fusarium oxysporum, Corynespora cassiicola, and Botrytis cinerea.
机译:合成了新的1,3,4-噻二唑化合物JV-(5-(邻甲苯基)-1,3,4-噻二唑-2-基)环丙烷甲酰胺,并通过〜1 H NMR,MS和HRMS。通过X射线衍射确定标题化合物的单晶结构。初步的生物学测试表明,合成的化合物对芸苔属油菜具有适度的除草活性,对大麦核盘菌,茄形丝枯菌,尖孢镰刀菌,小菜蛾和灰霉病菌具有中等的除草活性。

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