Introducing the delayed retinoid burn: a case report and discussion of this potential risk of retinoid-phototherapy combination management.

摘要

Combination treatment with an oral retinoid and phototherapy, including narrowband UVB (NB-UVB) and PUVA, is highly effective in psoriasis.1'2 However, there is a unique risk for phototoxicity when a systemic retinoid is added to an already maximized phototherapy dosimetry. We have encountered this phenomenon many times over the years to the extent that a preventative measure is part of the standard protocol at our phototherapy unit. To our knowledge, this phototoxicity risk has not been described in the medical literature. We illustrate this phenomenon below.