Efficacy of florfenicol for treatment of naturally occurring infectious bovine keratoconjunctivitis.

摘要

63 beef calves and 80 dairy calves between 4 and 12 months of age were used to study the efficacy of florfenicol for treatment of calves with naturally occurring infectious bovine keratoconjunctivitis (IBK). Calves were randomly assigned to 1 of 3 treatment groups. Calves in the s.c. treatment group received a single dose of florfenicol (40 mg/kg body weight) s.c. on day 0. Calves in the i.m. treatment group received florfenicol (20 mg/kg) i.m. on days 0 and 2. Calves in the control group receivedinjections of saline solution (0.9% NaCl) i.m. on days 0 and 2. Calves were re-evaluated every other day for 20 days after treatment. Corneal ulcers healed by day 20 in 48 of 49 (98%) calves treated with florfenicol i.m., 39 of 42 (93%) calves treated with florfenicol s.c. and 33 of 52 (63%) control calves. It is concluded that florfenicol administered SC (1 dose) or IM (2 doses 48 hours apart) is effective for treatment of calves with naturally occurring IBK.