Atypical effects of incorporated surfactants on stability and dissolution properties of amorphous polymeric dispersions

Al-Obaidi Hisham; Lawrence M. Jayne; Buckton Graham

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Atypical effects of incorporated surfactants on stability and dissolution properties of amorphous polymeric dispersions

机译：掺入的表面活性剂对非晶态聚合物分散体稳定性和溶解性的非典型影响

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Objectives To understand the impact of ionic and non-ionic surfactants on the dissolution and stability properties of amorphous polymeric dispersions using griseofulvin (GF) as a model for poorly soluble drugs.

机译：目的使用灰黄霉素（GF）作为难溶性药物的模型，了解离子型和非离子型表面活性剂对非晶态聚合物分散体溶解和稳定性的影响。

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来源
《Journal of Pharmacy and Pharmacology》 |2016年第11期|共11页
作者
Al-Obaidi Hisham; Lawrence M. Jayne; Buckton Graham;
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正文语种 eng
中图分类药理学;
关键词
dissolution rate; glass transition temperature; globules; solid dispersions; spray drying; surfactants;

机译：溶解速率;玻璃化转变温度;小球;固体分散体;喷雾干燥;表面活性剂;

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1. Atypical effects of incorporated surfactants on stability and dissolution properties of amorphous polymeric dispersions [J] . Al-Obaidi Hisham, Lawrence M. Jayne, Buckton Graham Journal of Pharmacy and Pharmacology . 2016,第11期

机译：掺入的表面活性剂对非晶态聚合物分散体稳定性和溶解性的非典型影响
2. Amorphous Stabilization and Dissolution Enhancement of Amorphous Ternary Solid Dispersions: Combination of Polymers Showing Drug-Polymer Interaction for Synergistic Effects [J] . Prasad Dev, Chauhan Harsh, Atef Eman Journal of pharmaceutical sciences. . 2014,第11期

机译：非晶稳定和溶解增强的三元固体分散体：聚合物的组合显示药物-聚合物相互作用的协同作用。
3. Solid-state properties, solubility, stability and dissolution behaviour of co-amorphous solid dispersions of baicalin [J] . Jangid Ashok Kumar, Jain Poonam, Medicherla Kanakaraju, CrystEngComm . 2020,第37期

机译：黄芩苷共 - 无定形固体分散体的固态性质，溶解度，稳定性和溶解行为
4. Effect of Oils and Surfactants on Solid Dispersions of Various Cellulose Polymers For Dissolution Enhancement of Poorly Soluble Drugs(Abstract) [C] . Yogesh M. Rane, Rajashree C. Mashru PMSE Symposia . 2005

机译：油和表面活性剂对各种纤维素聚合物固体分散体的影响，用于溶解溶于可溶性药物的溶解增强（摘要）
5. Roles of Surfactant and Binary Polymers on Dissolution Enhancement of BCS II Drugs from Nanocomposites and Amorphous Solid Dispersions [D] . Rahman, Md. Mahbubur. 2019

机译：表面活性剂和二元聚合物对纳米复合材料和无定形固体分散体溶解增强的作用
6. The Effects of Polymer Carrier Hot Melt Extrusion Process and Downstream Processing Parameters on the Moisture Sorption Properties of Amorphous Solid Dispersions [O] . Xin Feng, Anh Vo, Hemlata Patil, -1

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7. Multiple Linear Regression Modeling To Predict the Stability of Polymer–Drug Solid Dispersions: Comparison of the Effects of Polymers and Manufacturing Methods on Solid Dispersion Stability [O] . Gudrun A. Fridgeirsdottir, Robert J. Harris, Ian L. Dryden, 2018

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8. Effect of polymer-surfactant interaction on the rheological properties of surfactant enhanced alkaline flooding formulations [R] . French, T. R., Josephson, C. B. 1993

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Atypical effects of incorporated surfactants on stability and dissolution properties of amorphous polymeric dispersions

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