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Survival advantage in trauma centers: expeditious intervention or experience?

机译:创伤中心的生存优势:迅速的干预或经验?

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BACKGROUND: Trauma patients who receive care at designated trauma centers have a decreased risk of death, but the processes of care that lead to improved outcomes are unknown. We set out to examine the relationship between trauma center care, rapidity of assessment and intervention, and mortality among trauma patients with indications for immediate operative intervention. STUDY DESIGN: Data were collected from a multicenter prospective cohort study of adult patients cared for in trauma centers (TC) and nondesignated centers (NTC). From this cohort, we identified patients with two patterns of injury: hypotensive penetrating trauma (PT) and blunt traumatic brain injury (TBI) with mass effect. Times from admission to relevant interventions were assessed, as were relative risks of in-hospital death in TC compared with NTC. Relative risks were adjusted for differences in case mix using propensity analysis. RESULTS: Among 1,331 patients who met inclusion criteria, 23.5% died in hospital. Relative risk of death was 0.61 (95% CI, 0.43 to 0.86) among patients managed at TC compared with those admitted to NTC. This survival advantage was greatest among patients in the PT group managed at TC (relative risk: 0.43; 95% CI, 0.19 to 0.94). Relative risk of death at TC among patients in the TBI group was 0.72 (95% CI, 0.50 to 1.0). Within the first 24 hours of admission, however, there was no statistically significant difference between median times to radiographic assessment or operative intervention at TC as compared with other hospitals. CONCLUSIONS: Risk of death is considerably lower among patients requiring early operative intervention if they are treated at a designated Level I trauma center. These outcomes are not a result of more rapid assessment and intervention alone, and emphasize the complex factors that contribute to the survival benefit of trauma center care.
机译:背景:在指定的创伤中心接受护理的创伤患者的死亡风险降低,但导致结果改善的护理过程尚不清楚。我们着手检查创伤中心护理,评估和干预的速度以及创伤患者之间的死亡率之间的关系,并指出需要立即进行手术干预。研究设计:数据来自对创伤中心(TC)和非指定中心(NTC)所照顾的成年患者的多中心前瞻性队列研究。从这个队列中,我们确定了具有两种损伤模式的患者:具有整体效应的低血压穿透性创伤(PT)和钝性创伤性脑损伤(TBI)。评估从入院到相关干预的时间,以及与NTC相比,TC中院内死亡的相对风险。使用倾向分析针对病例组合的差异调整了相对风险。结果:在符合入选标准的1,331例患者中,有23.5%在医院死亡。与接受NTC治疗的患者相比,接受TC治疗的患者的相对死亡风险为0.61(95%CI,0.43至0.86)。在接受TC治疗的PT组患者中,这种生存优势最大(相对风险:0.43; 95%CI,0.19至0.94)。 TBI组患者TC死亡的相对风险为0.72(95%CI,0.50至1.0)。然而,在入院的最初24小时内,与其他医院相比,在TC的放射线评估或手术干预的中位时间之间,在统计学上没有显着差异。结论:如果在指定的I级创伤中心接受治疗,需要早期手术干预的患者中的死亡风险要低得多。这些结果并不是单独进行更快速评估和干预的结果,而是强调了有助于创伤中心护理生存的复杂因素。

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