Endothelin-1 release and stimulation of the inflammatory cascade: is acute coronary syndrome triggered by watching spectator sports?

摘要

Exposure to acute emotional stress can occur at any time; indeed, some of us buy tickets to it (1). Regardless of how people are exposed to acute emotional stress, elevated risk of acute coronary syndrome (ACS) can follow (2-4). The role of acute stress in the triggering of cardiovascular events is no longer disputed, thanks to carefully conducted prospective cohort studies (3,5,6). Specific behaviors (e.g., cocaine use and intense physical activity), environmental events (e.g., natural disasters), and emotional reactions (e.g., anger and sadness) have been identified that increase the risk of ACS for a distinct hazard period (2,3).