Chemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal 'mushroom'

摘要

Ethnopharmacological relevance: In Russian traditional medicine, an extract from the mushroom Inonotus obliquus (Fr.) Pil at is used as an anti-tumor medicine and diuretic. It has been reported that Inonotus obliquus has therapeutic effects, such as anti-inflammatory, immuno-modulatory and hepatoprotective effects. This study was designed to investigate the chemical composition and biological properties of aqueous and ethanolic extracts of Inonotus obliquus from Finland, Russia, and Thailand. Their antioxidative, antimicrobial, and antiquorum properties were tested as well as the cytotoxicity on various tumor cell lines.