Pancreatic Acinar Cell Carcinoma with Diffuse Whole-organ Involvement: an unusual presenting pattern

摘要

Pancreatic acinar cell carcinoma is a rare tumor arising from exocrine components of pancreas. Several case reports and case series studies have reported the imaging characteristics of the pancreatic acinar cell carcinoma, I including computed tomography (CT) and magnetic resonance imaging (MRI). It is generally considered to be an exophytic, well-circumscribed mass arising from pancreas without pancreatic ductal dilatation. We report an unusual case of pancreatic acinar cell carcinoma with diffuse organ involvement initially mimicking a duodenal tumor. The diagnosis was confirmed histologically after a total pancreatectomy and the specimen showed diffuse pancreatic involvement of the tumor. To the best of our knowledge, diffuse whole-organ involvement of pancreatic acinar cell carcinoma has never been reported in the scientific literature.