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Diagnostic criteria of inflammatory bowel disease.

机译:炎性肠病的诊断标准。

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摘要

We read with great interest with the case report presented by Shehzad Sheikh et al. [1], but we are confused with the diagnosis of Crohn's disease (CD). How the diagnosis of CD was established after restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA). Maybe it was just the recurrence of the ulcerative colitis (UC). The Pouchoscopy revealed deep ulcerations, stenosis in the pouch and afferent ileum, but the biopsies just revealed the presence of active inflammatory bowel disease (IBD) consisting of UC and CD. Pouch strictures after IPAA are common. Strictures may occur in over 10% of patients with IPAA for UC [2]. The positive perinuclear anti-neutrophil cytoplasmic anti-body (pANCA) just suggests IBD, and it is more prevalent in UC [3]. Herebywe discuss diagnostic criteria of IBD from Western and Asian.Mendeloffs criteria [4], Lennard-Jones criteria [5] are widely used for IBD in Western countries. Mendeloff emphasized that a definite diagnosis of UC should be based on a clinical course of more than six weeks, rule out other disease with a combination of endoscopic, radiological and pathological features. If any one of these was dubious, the diagnosis is regarded as 'probable' only; a definite diagnosis of CD needs typical histopathological findings.
机译:我们对Shehzad Sheikh等人提交的病例报告非常感兴趣。 [1],但我们对克罗恩病(CD)的诊断感到困惑。经回肠小肠肛门吻合术(IPAA)进行的直肠结肠切除术后如何确定CD的诊断。也许仅仅是溃疡性结肠炎(UC)的复发。胃镜检查显示出溃疡深处,眼袋狭窄和回肠传入,但活检仅显示存在由UC和CD组成的活动性炎症性肠病(IBD)。 IPAA之后的囊袋狭窄很常见。患有IPAA的UC患者中有10%以上会出现狭窄[2]。阳性的核周抗中性粒细胞胞浆抗体(pANCA)仅提示IBD,并且在UC中更为普遍[3]。因此,我们从西方和亚洲人讨论了IBD的诊断标准。Mendeloffs标准[4],Lennard-Jones标准[5]在西方国家被广泛用于IBD。 Mendeloff强调,对UC的明确诊断应基于六个多星期的临床过程,排除具有内镜,放射学和病理学特征的其他疾病。如果其中任何一个是可疑的,则诊断仅被认为是“可能”。明确的CD诊断需要典型的组织病理学发现。

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