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Modern outcomes of oesophageal atresia: Single centre experience over the last twenty years

机译:食管闭锁的现代预后:过去二十年的单中心经验

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Aim of the Study The aim of this study was assessment of the contemporary outcomes of oesophageal atresia (OA) in a national paediatric surgical centre. Patients and Methods A review of the hospital records of all patients who underwent repair of oesophageal atresia (OA) in our institute between 1991 and 2011 was performed. Results The study included 130 consecutive infants with OA: types A (n = 4, 3%), B (n = 2, 2%), C (n = 110, 85%), D (n = 5, 4%), and E (n = 9, 7%). Median follow-up was 8.8 (range 0.1-21) years. Twenty-nine (22%) infants had cardiac and 76 (58%) other anomalies, and seventeen (13%) had a long-gap OA. The final repair was primary (n = 113, 87%) or delayed (n = 3) end-to-end anastomosis, oesophageal replacement (n = 8) (6%) with gastric tube (n = 4) or with jejunum interposition (n = 4), and closure of the trachea-oesophageal fistula (Type E, n = 9). Oesophageal continuity was achieved in all patients. Overall mortality was 3/130 (2%) and caused by gastric perforation (n = 1), prolonged apnoeic spell (n = 1), and food asphyxiation (n = 1). Oral feeds were achieved in 121 (94%) children. Eight (6%) children remain dependent on feeding ostomy. Long-gap OA was a major predictor of post-repair complications. Conclusion The modern outcome for infants with OA is characterized by an extremely low hospital mortality and satisfactory oesophageal function, enabling full oral feeds in the vast majority of children. ? 2013 Elsevier Inc.
机译:研究的目的本研究的目的是评估国家小儿外科中心食管闭锁(OA)的当代疗效。患者与方法回顾性分析了我院1991年至2011年间所有接受食管闭锁(OA)修复的患者的医院记录。结果研究包括130例连续的OA婴儿:A型(n = 4,3%),B型(n = 2,2%),C型(n = 110,85%),D型(n = 5,4%) ,和E(n = 9,7%)。中位随访时间为8.8年(范围0.1-21)。 29例(22%)婴儿有心脏异常,其他76例(58%)异常,而17例(13%)患有长间隙OA。最终修复为初次(n = 113,87%)或延迟(n = 3)端到端吻合术,食道置换(n = 8)(6%)胃管(n = 4)或空肠插入(n = 4),并关闭气管食管瘘(E型,n = 9)。所有患者均达到食管连续性。总体死亡率为3/130(2%),由胃穿孔(n = 1),延长的催眠药(n = 1)和食物窒息(n = 1)引起。 121名(94%)儿童获得了口服饲料。八(6%)名儿童仍然依赖于喂养造口术。长间隙OA是修复后并发症的主要预测指标。结论OA婴儿的现代预后特点是极低的住院死亡率和令人满意的食道功能,可为绝大多数儿童提供全面的口服食物。 ? 2013爱思唯尔公司

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