Rapid improvement of diffusion-weighted imaging abnormalities after glucose infusion in hypoglycaemic coma.

摘要

Diffusion-weighted imaging (DWI) may detect hyperintense lesions in patients with transient hypoglycaemia-induced hemiparesis or coma, which are completely reversible after glucoseinfusion. In vivo animal studies have documented the visualisation of such hypoglycaemia-induced changes of signal intensity and the reversal by glucose intake in detail. However, the time necessary for hyperintense lesions on DWI to disappear after glucose infusion in humans is still unclear. We treated a patient in a hypoglycaemic coma with DWI abnormalities in the splenium of the corpus callosum and the bilateral posterior limbs of the internal capsules, which were drastically improved 2 h after glucose infusion.