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首页> 外文期刊>Journal of Neurology, Neurosurgery and Psychiatry >Visual prognosis after indirect traumatic optic neuropathy.
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Visual prognosis after indirect traumatic optic neuropathy.

机译:间接创伤性视神经病变后的视觉预后。

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OBJECTIVE: To investigate a possible correlation between final visual acuity and the presence at baseline of various systemic and local (orbital/ocular) signs in patients affected by indirect traumatic optic neuropathy. METHODS: 35 cases of traumatic optic neuropathy were examined retrospectively and 13 variables were tested. Univariate analysis with "no recovery of visual acuity" as the primary outcome was performed. Relative risk (RR) and 95% confidence intervals (CI) were calculated. Fisher's exact test was used for two variables to test differences between proportions. RESULTS: Four variables showed a significantly increased risk for no recovery of visual acuity: presence of blood within the posterior ethmoidal cells (RR = 2.25, 95% CI 1.25 to 4.04); age over 40 years (RR = 1.79, 1.07 to 2.99); loss of consciousness associated with traumatic optic neuropathy (RR = 2.21, 1.17 to 4.16); and absence of recovery after 48 hours of steroid treatment (p < 0.01, Fisher's exact test). Recovery documented atthe first follow up visit after treatment was significantly associated with recovery at the last follow up visit (p < 0.01, Fisher's exact test). CONCLUSIONS: These four negative prognostic signs in patients affected by traumatic optic neuropathy may be useful in predicting the visual outcome in patients developing visual loss after head trauma and in deciding on the need for surgical treatment.
机译:目的:探讨间接外伤性视神经病变患者的最终视敏度与基线时各种全身和局部(眼眶/眼)体征的存在之间的可能相关性。方法:回顾性分析35例外伤性视神经病变的病例,并测试13个变量。进行以“视力无恢复”为主要结果的单因素分析。计算相对风险(RR)和95%置信区间(CI)。 Fisher精确检验用于两个变量,以检验比例之间的差异。结果:四个变量显示无法恢复视力的风险显着增加:筛骨后细胞内存在血液(RR = 2.25,95%CI 1.25至4.04);年龄超过40岁(RR = 1.79,1.07至2.99);与外伤性视神经病变相关的意识丧失(RR = 2.21,1.17至4.16);类固醇治疗48小时后无恢复(p <0.01,Fisher精确检验)。治疗后首次随访记录的恢复与末次随访记录的恢复显着相关(p <0.01,Fisher精确检验)。结论:受外伤性视神经病变影响的这四个阴性预后体征可能有助于预测颅脑外伤后视力丧失的患者的视力结果,并决定是否需要手术治疗。

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