Primary vesicoureteric reflux grade i to V: No compelling evidence for routine antibiotics or surgical intervention

摘要

Long-term low-dose antibiotic prophylaxis showed a nonsignificant trend to reduced repeat symptomatic urinary tract infection (UTI) (846 children; risk ratio (RR) 0.68, 95% confidence interval (CI) 0.39 to 1.17) and febrile UTI in children with VUR (946 children; RR 0.77, 95% CI 0.47 to 1.24) when compared with placebo and surveillance (Fig. 1). These findings are largely consistent with those of a related review in children unselected for the presence of VUR.