Solid-phase photosensitizers based on fullerene C_(60) for photodynamic inactivation of viruses in biological liquids

摘要

A new type of solid-phase photosensitizer has been proposed and created on the basis of aggre_gated fullerene C_(60) for the photodynamic inactivation of pathogens in biological liquids. This paper demonstrates the chief advantage of such solid-phase systems, which is that efficient inac_tivation of pathogens (using influenza viruses as an example) by active forms of oxygen formed when a photosensitizer is irradiated in aqueous and biological media is combined with high pho_tostability of the fullerene coatings and the possibility of completely extracting the photosensi_tizer from the biological medium after photodynamic activation.