首页> 外文期刊>Journal of Neurosurgery. Spine. >Reduced postoperative wound pain after lumbar spinous process-splitting laminectomy for lumbar canal stenosis: a randomized controlled study.
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Reduced postoperative wound pain after lumbar spinous process-splitting laminectomy for lumbar canal stenosis: a randomized controlled study.

机译:减轻腰椎管狭窄椎板切除术治疗腰椎管狭窄症后的术后伤口疼痛:一项随机对照研究。

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OBJECT: to reduce intraoperative damage to the posterior supporting structures of the lumbar spine during decompressive surgery for lumbar canal stenosis (LCS), lumbar spinous process-splitting laminectomy (LSPSL or split laminectomy) was developed. This prospective, randomized, controlled study was conducted to clarify whether the split laminectomy decreases acute postoperative wound pain compared with conventional laminectomy. METHODS: forty-one patients with LCS were enrolled in this study. The patients were randomly assigned to either the LSPSL group (22 patients) or the conventional laminectomy group (19 patients). Questionnaires regarding wound pain (intensity, depth, and duration) and activities of daily living (ADL) were administered at postoperative days (PODs) 3 and 7. Additionally, the authors evaluated the pre- and postoperative serum levels of C-reactive protein and creatine phosphokinase, the amount of pain analgesics used during a 3-day postoperative period, and the muscle atrophy rate measured on 1-month postsurgical MR images. RESULTS: data obtained in patients in the LSPSL group and in 16 patients in the conventional laminectomy group were analyzed. The mean visual analog scale for wound pain on POD 7 was significantly lower in the LSPSL group (16 +/- 17 mm vs 34 +/- 31 mm, respectively; p = 0.04). The mean depth-of-pain scores on POD 7 were significantly lower in the LSPSL group than in the conventional group (0.9 +/- 0.6 vs 1.7 +/- 0.8, respectively; p = 0.013). On POD 3, the mean serum creatine phosphokinase level was significantly lower in the LSPSL group (126 +/- 93 U/L) than in the other group (207 +/- 150 U/L) (p = 0.02); on POD 7, the mean serum C-reactive protein level was significantly lower in the LSPSL group (1.1 +/- 0.6 mg/dl) than in the conventional laminectomy group (1.9 +/- 1.5 mg/dl) (p = 0.04). The number of pain analgesics taken during the 3-day postoperative period was lower in the LSPSL group than in the conventional laminectomy group (1.7 +/- 1.3 tablets vs 2.3 +/- 2.4 tablets, respectively; p = 0.22). The mean muscle atrophy rate was also significantly lower in the LSPSL group (24% +/- 15% vs 43% +/- 22%; p = 0.004). CONCLUSIONS: lumbar spinous process-splitting laminectomy for the treatment of LCS reduced acute postoperative wound pain and prevented postoperative muscle atrophy compared with conventional laminectomy, possibly because of minimized damage to the paraspinal muscles.
机译:目的:为减少在减压治疗腰椎管狭窄症(LCS)时对腰椎后支撑结构的术中损害,开发了腰椎棘突劈开椎板切除术(LSPSL或劈开椎板切除术)。这项前瞻性,随机对照研究旨在阐明与常规椎板切除术相比,劈开椎板切除术是否可以减轻急性术后伤口疼痛。方法:41例LCS患者入选本研究。将患者随机分为LSPSL组(22例)或常规椎板切除术组(19例)。在术后第3天和第7天进行关于伤口疼痛(强度,深度和持续时间)和日常生活活动(ADL)的问卷调查。此外,作者评估了术前和术后血清C反应蛋白和肌酸磷酸激酶,术后3天使用的止痛药量以及术后1个月MR图像测量的肌肉萎缩率。结果:分析了LSPSL组和常规椎板切除术组16例患者获得的数据。在LSPSL组中,POD 7上伤口疼痛的平均视觉模拟评分明显较低(分别为16 +/- 17 mm和34 +/- 31 mm; p = 0.04)。 LSPSL组中POD 7的平均疼痛深度得分显着低于常规组(分别为0.9 +/- 0.6和1.7 +/- 0.8; p = 0.013)。在POD 3上,LSPSL组的平均血清肌酸磷酸激酶水平(126 +/- 93 U / L)显着低于其他组(207​​ +/- 150 U / L)(p = 0.02)。在POD 7上,LSPSL组的平均血清C反应蛋白水平(1.1 +/- 0.6 mg / dl)显着低于常规椎板切除术组(1.9 +/- 1.5 mg / dl)(p = 0.04) 。 LSPSL组术后3天服用止痛药的次数低于常规椎板切除术组(分别为1.7 +/- 1.3片和2.3 +/- 2.4片; p = 0.22)。 LSPSL组的平均肌肉萎缩率也显着降低(24%+/- 15%vs 43%+/- 22%; p = 0.004)。结论:与常规椎板切除术相比,腰椎棘突劈开椎板切除术治疗LCS可以减轻急性术后伤口疼痛并预防术后肌肉萎缩,这可能是因为对椎旁副肌的损伤最小。

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