-)-6-Chloro-2-((1-furo(2, 3-c)pyridin-5-ylethyl)thio)-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.

Wishka DG; Graber DR; Kopta LA; Olmsted RA; Friis JM; Hosley JD; Adams WJ; Seest EP; Castle TM; Dolak LA; Keiser BJ; Yagi Y; Jeganathan A; Schlachter ST; Murphy MJ; Cleek GJ; Nugent RA; Poppe SM; Swaney SM; Han F; Watt W; White WL; Poel TJ; Thomas RC; Morris J; et al

首页> 外文期刊>Journal of Medicinal Chemistry >-)-6-Chloro-2-((1-furo(2, 3-c)pyridin-5-ylethyl)thio)-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.

【24h】

-)-6-Chloro-2-((1-furo(2, 3-c)pyridin-5-ylethyl)thio)-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.

机译：-）-6-Chloro-2-（（（1-furo（2，3-c）pyridin-5-ylethyl）thio）-4-pyrimidinamine，PNU-142721，一种新型广谱HIV-1非核苷逆转录酶抑制剂。

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

团队文献服务 >>

页面导航

著录项
相似文献
相关主题

著录项

来源
《Journal of Medicinal Chemistry 》 |1998年第9期| 共4页
作者
Wishka DG; Graber DR; Kopta LA; Olmsted RA; Friis JM; Hosley JD; Adams WJ; Seest EP; Castle TM; Dolak LA; Keiser BJ; Yagi Y; Jeganathan A; Schlachter ST; Murphy MJ; Cleek GJ; Nugent RA; Poppe SM; Swaney SM; Han F; Watt W; White WL; Poel TJ; Thomas RC; Morris J; et al;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药学 ;
关键词
Anti-HIV Agents; HIV-1; Pyridines; Pyrimidines; Reverse Transcriptase Inhibitors; 抗HIV药; HIV-1; 吡啶类; 嘧啶类; 逆转录酶抑制剂;

机译：Anti-HIV Agents;HIV-1;Pyridines;Pyrimidines;Reverse Transcriptase Inhibitors;抗HIV药;HIV-1;吡啶类;嘧啶类;逆转录酶抑制剂;

相似文献

外文文献
中文文献
专利

1. -)-6-Chloro-2-((1-furo(2, 3-c)pyridin-5-ylethyl)thio)-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor. [J] . Wishka DG, Graber DR, Kopta LA, Journal of Medicinal Chemistry . 1998 ,第9期

机译：-）-6-Chloro-2-（（（1-furo（2，3-c）pyridin-5-ylethyl）thio）-4-pyrimidinamine，PNU-142721，一种新型广谱HIV-1非核苷逆转录酶抑制剂。
2. Optical resolution of (+-)-1-furo[2,3-c]pyridin-5-yl-ethanol using extraction technique: formal total synthesis of PNU-142721, HIV-1 reverse transcriptase inhibitor [J] . Masato Matsugi, Kinuyo Itoh, Masatomo Nojima, Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2003 ,第16期

机译：（+-）-1-呋喃并[2,3-c]吡啶-5-基-乙醇的光学拆分，采用萃取技术：PNU-142721，HIV-1逆转录酶抑制剂的正式全合成
3. New indolylarylsulfones as highly potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors [J] . Valeria Famiglini, Giuseppe La Regina, Antonio Coluccia, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2014 ,第Null期

机译：新的吲哚基芳砜作为高效和广谱的HIV-1非核苷逆转录酶抑制剂
4. A Novel Detection of Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs) for HIV-1 with AlGaN/GaN High Electron Mobility Transistors [C] . Yen-Wen Kang, Geng-Yen Lee, Jen-Inn Chyi, Symposium on wide bandgap semiconductor materials and devices;Meeting of the Electrochemical Society . 2013

机译：AlGaN / GaN高电子迁移率晶体管对HIV-1的非核苷逆转录酶抑制剂（NNRTIs）的新型检测
5. Target specificity and structural characterization of single-stranded DNA aptamer RT1t49, a broad inhibitor of HIV-1 reverse transcriptases. [D] . Kissel, Jay D. 2007

机译：具有特异性的HIV-1逆转录酶抑制剂单链DNA适体RT1t49的靶标特异性和结构特征。
6. Effect of template secondary structure on the inhibition of HIV-1 reverse transcriptase by a pyridinone non-nucleoside inhibitor. [O] . D B Olsen, S S Carroll, J C Culberson, 1994

机译：模板二级结构对吡啶酮非核苷抑制剂抑制HIV-1逆转录酶的影响。
7. Indolylarylsulfones carrying a heterocyclic tail as very potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors [O] . Famiglini, Valeria, La Regina, Giuseppe, Coluccia, Antonio, 2014

机译：带有杂环尾部的吲哚基芳基砜是非常有效的广谱HIV-1非核苷逆转录酶抑制剂

-)-6-Chloro-2-((1-furo(2, 3-c)pyridin-5-ylethyl)thio)-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.

著录项

相似文献

相关主题

期刊订阅