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Quality of life following surgery of ascending aorta and aortic arch with selective antegrade cerebral perfusion

机译:选择性主动脉灌注治疗升主动脉和主动脉弓手术后的生活质量

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Objective Surgery of the ascending aorta and aortic arch has been challenging since its inception as neurological complications may occur significantly affecting the quality of life (QOL). Methods From January 1998 to December 2007, 79 patients mainly suffering aortic dissection (65%) or true aortic aneurysm (34%) underwent surgery on the aortic arch employing deep hypothermic circulatory arrest and selective antegrade cerebral perfusion. QOL was assessed with the sickness-impact-profile (SIP) comprising 136 questions and 12 categories. Results All patients underwent replacement of the ascending aorta, combined with a partial (hemiarch) (n = 33; 42%) or total (n = 46, 58%) arch replacement. Thirty-day mortality was 17.7% (n = 14 patients). Perioperatively, three patients (3.8%) suffered a transitory ischemic attack (TIA) and 5.1% patients suffered a stroke. The median score of the complete questionnaire was 4.7, which demonstrates excellent QOL following such complex surgical procedures. The median physical dimension was 2.5 (0; 8), the psychosocial median score was 3.7 (1.2; 16.1), both underline an only minimal impairment of the daily life. Conclusion The QOL after following the surgery of ascending aorta and aortic arch with selective antegrade cerebral perfusion is excellent on the long-term as assessed by the SIP.
机译:客观由于升神经和并发症可能会严重影响生活质量(QOL),因此升主动脉和主动脉弓的手术一直具有挑战性。方法1998年1月至2007年12月,对79例主要为主动脉夹层(65%)或真主动脉瘤(34%)的患者进行了深低温循环停止和选择性顺行脑灌注的主动脉弓手术。使用包括136个问题和12个类别的疾病影响档案(SIP)对生活质量进行了评估。结果所有患者均接受升主动脉置换,部分(弓形)(n = 33; 42%)或全部(n = 46,58%)弓置换。 30天死亡率为17.7%(n = 14例患者)。围手术期,三名患者(3.8%)遭受了短暂性脑缺血发作(TIA),而5.1%的患者患有中风。完整问卷的中位数为4.7,表明在进行此类复杂的手术后其QOL极好。中位物理维度为2.5(0; 8),社会心理中位得分为3.7(1.2; 16.1),都突显了对日常生活的最小损害。结论SIP评估,升主动脉和主动脉弓伴选择性顺行性脑灌注术后的QOL从长期来看是极好的。

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