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Interventional catheterization after total cavopulmonary connection: Experience in 68 patients

机译:全腔肺连接后介入导管插入术:68例经验

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Background: Total cavopulmonary connection (TCPC) is performed in patients having a single ventricle to allow the passive flow of systemic venous blood to the lungs. Interventional catheterization is needed to treat residual defects or complications. Aims: We discuss our results concerning 68 patients who had had TCPC from January 1995 to December 2010. Methods: Initial and follow-up catheterization data were reviewed retrospectively. Mid-term results were evaluated by means of angiography and/or CT scan. Results: Mean age at TCPC was 5 years (2.5-18); mean interval between TCPC and catheterization was 5.6 years (1.5-15). Sixty-nine catheterizations were performed in 53 patients. Eleven patients (21%) had low venous pressure, did not display a right-to-left shunt, and did not need any intervention. Fifteen patients (28%) had low venous pressure and only needed the closure of the fenestration. The remaining 27 patients (51%) needed the following interventions: embolization of venous vessels prompting right-to-left shunt (n = 15), stenting or reconnection of pulmonary arteries (n = 5), stenting or recanalization of systemic veins (n = 11), other procedures (n = 5). In 3 patients the fenestration could not be closed due to high venous pressure. After the interventions oxygen saturation increased from 90.5%± 4.8% to 94.7%± 3.6% (P = 0.002). Conclusions: Our data show that 49% of patients with TCPC are in good condition late after surgery. However, half of these patients continue to need interventions generally aimed at suppressing stenoses at various levels of TCPC or at occluding vessels prompting right-to-left shunt. This population should enter a multicenter program aimed at identifying patients at risk.
机译:背景:全心肺连接(TCPC)是在具有单个心室的患者中进行的,以允许全身性静脉血液被动流向肺部。需要介入导管术以治疗残留的缺陷或并发症。目的:我们讨论了1995年1月至2010年12月期间68例TCPC患者的研究结果。方法:回顾性分析初始和后续导管插入数据。通过血管造影和/或CT扫描评估中期结果。结果:TCPC的平均年龄为5岁(2.5-18); TCPC和导管插入术之间的平均间隔为5.6年(1.5-15)。 53名患者进行了69次导管插入术。 11名患者(21%)的静脉压低,没有显示从右到左的分流,并且不需要任何干预。 15名患者(28%)静脉压低,只需要关闭开窗即可。其余27位患者(51%)需要以下干预措施:促使右向左分流的静脉血管栓塞(n = 15),肺动脉支架置入或重新连接(n = 5),系统静脉支架置入或再通(n = 11),其他程序(n = 5)。在3例患者中,由于高静脉压,无法开窗。干预后,血氧饱和度从90.5%±4.8%增加到94.7%±3.6%(P = 0.002)。结论:我们的数据显示,术后晚期晚期TCPC患者中有49%处于良好状态。但是,这些患者中有一半继续需要采取干预措施,通常旨在抑制TCPC各个级别的狭窄或阻塞血管,促使血管从右向左分流。该人群应参加旨在识别高危患者的多中心计划。

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