European Society of Hypertension Working Group on Obesity: obesity drugs and cardiovascular outcomes.

摘要

Obesity is a common comorbidity in patients with arterial hypertension. Indeed, approximately 75% of the hypertensive patients seen by general practitioners or internists are overweight or obese [1]. Even though obese hypertensive patients are often prescribed more antihyperten-sive medications, their blood pressure tends to be less well controlled. Given the worldwide epidemic increase in obesity, the number of obese hypertensive patients is likely to increase further. Given that obesity also increases the risk for type 2 diabetes mellitus, dyslipi-demia, and other metabolic and cardiovascular ailments, obese hypertensive patients require comprehensive interdisciplinary care. Lifestyle interventions are indispensable and provide the first line of treatment. Indeed, moderate weight loss through caloric restriction and physical exercise induces a massive and sustained reduction in type 2 diabetes mellitus incidence [2,3].