Incremental diagnostic value of F-18 FDG PET/CT over MRI in a pediatric patient with suspected hepatoblastoma and histologic diagnosis of focal nodular hyperplasia.

摘要

Hepatoblastoma (HB) is the most common pediatric liver cancer representing 1% of all pediatric malignances and occurring mostly within 5 years of age. Liver recurrences and secondary lesions (abdomen, lung, and brain) can occur. Surgery and chemotherapy are widely accepted. Focal nodular hyperplasia (FNH) is a benign, usually asymptomatic, and incidental hepatic tumor with an unclear etiology, good prognosis, and its clinic management should be conservative. FNH could be evaluated by ultrasonog-raphy, computed tomography, and magnetic resonance imaging. Nuclear medicine procedures do not have an effective role in evaluating HB/FNH but F-18 FDG PET/CT represents a new option. We report a case of a child with a lesion suspect for HB at magnetic resonance imaging and negative F-18 FDG PET/CT with histologic diagnosis of FNH after resection.