Genetic predisposition and increasing dietary fructose exposure: The perfect storm for fatty liver disease in Hispanics in the U.S.

摘要

As the prevalence of overall obesity has increased in much of the developed and developing world, non-alcoholic fatty liver disease (NAFLD) is of increasing concern. A study of autopsy samples found that 38% of obese children had NAFLD [1], showing that NAFLD is a critical issue for obese children as well as for adults. NAFLD may lead to non-alcoholic steatohepatitis, cirrhosis, and eventually hepatocarcinoma, and is also associated with the development of type 2 diabetes.