Optimisation of post-mortem cardiac computed tomography compared to optical coherence tomography and histopathology - Technical note

摘要

It is with interest that we read the recently published technical note from Precht et al. We agree with the authors that minimally invasive techniques hold considerable potential to enhance current imaging approaches to the post-mortem assessment of coronary artery disease. We have previously reported an intact cadaveric approach for minimally invasive post-mortem computed tomography coronary angiography (PMCTA) validated against histology [1]. Developing on this system we described the first use of post-mortem coronary optical coherence tomography virtual-histology in our intact cadaveric model [2]. Extending the use of these approaches holds the potential to substantially enhance the information obtained from PMCTA by providing a much higher resolution 3-dimensional geometry of cadaveric coronary arteries in healthy and diseased subjects.