A report on the activity and clinical outcomes of renal non-heart beating donor transplantation in the United Kingdom.

摘要

Brook NR, Waller JR, Richardson AC, Bradley JA, Andrews PA, Koffman G, Gok M, Talbot D, Nicholson ML. A report on the activity and clinical outcomes of renal non-heart beating donor transplantation in the United Kingdom. Clin Transplant 2004 DOI: 10.1111/j.1399-0012.2004.00287.x (c) Blackwell Munksgaard, 2004Abstract: The use of kidneys from non-heart beating donors (NHBDs) presents a paradox; whilst they provide more organs for transplantation, there is an increased risk of poor graft outcome, particularly in the short term. This study has highlighted the difference in early graft function and late graft survival between NHBD kidneys with short (controlled) and long (uncontrolled) warm ischaemic times. Whilst it would seem that it is preferable to use controlled donors only, their numbers are small. By employing a rational approach to the use of each of these types of kidney, such as structured viability assessment and risk analysis, it may be that the results of uncontrolled NHBD can be improved.