Erratum: Synthesis and evaluation of anti-inflammatory, analgesic, ulcerogenic and lipid peroxidation properties of new 2-(4-isobutylphenyl) propanoic acid derivatives (Journal of Enzyme Inhibition and Medicinal Chemistry (2012) 27: 1 (110-116) DOI: 10.3109/14756366.2011.578743)

摘要

CAs are ubiquitous enzymes, catalysing a physiologically crucial reaction, the reversible hydration of CO to HCO_ and H. These enzymes, as multiple iso-forms in most organisms studied so far, are involved in a wide range of physiological processes, being present in high amounts in most tissues, for example, in erythrocytes8. In mammals, these enzymes are involved in processes connected with respiration and transport of CO/HCO, pH and CO homeostasis, electrolyte secretion in a variety of tissues/organs, biosynthetic reactions (such as gluconeogenesis, lipogenesis and ureagenesis), bone resorption, calcification, tuniouri-genicity and many other physiological or pathological processes (thoroughly studied in many vertebrates), whereas in algae, plants and some bacteria they play an important role in photosynthesis and other biosynthetic reactions