Analysis of short- and long-term metabolic effects of growth hormone replacement therapy in adult patients with craniopharyngioma and non-functioning pituitary adenoma

Profka E.; Giavoli C.; Bergamaschi S.; Ferrante E.; Malchiodi E.; Sala E.; Verrua E.; Rodari G.; Filopanti M.; Beck-Peccoz P.; Spada A.

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Analysis of short- and long-term metabolic effects of growth hormone replacement therapy in adult patients with craniopharyngioma and non-functioning pituitary adenoma

机译：成年颅咽管瘤和功能性垂体腺瘤患者生长激素替代治疗的短期和长期代谢作用分析

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Purpose Adult patients operated for craniopharyngioma develop more frequently GH deficiency (GHD) than patients operated for non-functioning pituitary adenoma (NFPA). The aim of the study was to compare both short- (1 year) and long-term (5 years) effects of rhGH in 38 GHD adult patients (19 operated for Craniopharyngioma (CP) and 19 for NFPA).

机译：目的与非功能性垂体腺瘤（NFPA）手术相比，成年的颅咽管瘤患者发生GH缺乏症（GHD）的频率更高。该研究的目的是比较38位GHD成年患者（19例颅咽管瘤（CP）和NFPA 19例）对rhGH的短期（1年）和长期（5年）效果。

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《Journal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology 》 |2015年第4期| 共8页
作者
Profka E.; Giavoli C.; Bergamaschi S.; Ferrante E.; Malchiodi E.; Sala E.; Verrua E.; Rodari G.; Filopanti M.; Beck-Peccoz P.; Spada A.;
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正文语种 eng
中图分类内分泌腺疾病及代谢病 ;
关键词
GH deficiency; Craniopharyngioma; Glucose homeostasis; rhGH replacement;

机译：GH缺乏症;颅咽管瘤;葡萄糖稳态;rhGH替代;

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1. Analysis of short- and long-term metabolic effects of growth hormone replacement therapy in adult patients with craniopharyngioma and non-functioning pituitary adenoma [J] . Profka E., Giavoli C., Bergamaschi S., Journal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology . 2015 ,第4期

机译：成年颅咽管瘤和功能性垂体腺瘤患者生长激素替代治疗的短期和长期代谢作用分析
2. Growth hormone deficiency and replacement in patients with treated Cushing's Disease, prolactinomas and non-functioning pituitary adenomas: effects on body composition, glucose metabolism, lipid status and bone mineral density. [J] . Colson A, Brooke AM, Walker D, Hormone research . 2006 ,第6期

机译：已治疗的库欣病，泌乳素瘤和垂体功能不正常的腺瘤患者生长激素缺乏和替代：对身体组成，葡萄糖代谢，脂质状况和骨矿物质密度的影响。
3. Effects of growth hormone replacement therapy on metabolic and cardiac parameters, in adult patients with childhood-onset growth hormone deficiency. [J] . Jallad RS, Liberman B, Vianna CB, Growth hormone and IGF research: Official journal of the Growth Hormone Research Society and the International IGF Research Society . 2003 ,第2a3期

机译：生长激素替代疗法对儿童期生长激素缺乏的成年患者代谢和心脏参数的影响。
4. Tumor Shrinkage Assessed by Volumetric MRI in the Long Term Follow-Up after Fractionated Stereotactic Radiotherapy of Non-functioning Pituitary Adenoma [C] . Christine Kopp, Marilena Theodorou, Nektarios Poullos Mediterranean Conference on Medical and Biological Engineering and Computin . 2016

机译：在非功能性垂体腺瘤的分级立体定向放射后的长期随访中，体积MRI评估的肿瘤收缩
5. Bone mineral density, bone remodeling, insulin-like growth factors, hormone replacement therapy, and exercise training in postmenopausal women [D] . Milliken, Laura Ann. 1998

机译：绝经后妇女的骨矿物质密度，骨骼重塑，胰岛素样生长因子，激素替代疗法和运动训练
6. Impact of Long-Term Growth Hormone Replacement Therapy on Metabolic and Cardiovascular Parameters in Adult Growth Hormone Deficiency: Comparison Between Adult and Elderly Patients [O] . Elisabetta Scarano, Enrico Riccio, Teresa Somma, 2021

机译：长期生长激素替代治疗对成人生长激素缺乏的代谢和心血管参数的影响：成人和老年患者的比较
7. Baseline characteristics and response to 2 years of growth hormone replacement of hypopituitary patients with growth hormone deficiency due to adult-onset craniopharyngioma in comparison to patients with non-functioning pituitary adenoma: data from KIMS ( [O] . Verhelst, Johan, Kendall-Taylor, Pat, Erfurth, Eva Marie, 2005

机译：与无功能垂体腺瘤患者相比，成人发病的颅咽管瘤患者生长激素缺乏的2年生长激素替代的基线特征和反应：来自KIms的数据（

Analysis of short- and long-term metabolic effects of growth hormone replacement therapy in adult patients with craniopharyngioma and non-functioning pituitary adenoma

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