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False lumen occlusion for chronic dissection

机译:假性管腔阻塞,用于慢性剥离

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摘要

Currently, the primary treatment for distal aortic dissection is medical using anti-impulse therapy. Surgical intervention has been reserved for patients who develop complications, and increasingly this has been in the form of thoracic endovascular aortic repair (TEVAR). Results of TEVAR for acute complicated dissection have been excellent as compared to open surgical or medical therapy, but the results after TEVAR for chronic complicated dissection are mixed. This is especially true for patients with dissections that extend into the abdominal aorta (the most common presentation). When these patients are treated with simple TEVAR of the true lumen across the primary entry tear, they are still prone to have retrograde false lumen flow and pressuriza-tion from distal re-entry tears in the visceral segment of the aorta or iliac arteries. This is true even when the stent-graft is extended throughout the thoracic aorta to the level of the celiac artery. The backflow into the false lumen can lead to persistent risk of rupture even if it is slow flow not detectable during arterial phase computed tomography. Delayed venous phase imaging is critical in these patients to detect the slower retrograde flow that can contribute to excessive pressur-ization of the aneurysmal false lumen. Aortic dissection disease requires particularly complex treatment, and the currently available endovascular systems fall short during the chronic phase.
机译:当前,远端主动脉夹层的主要治疗方法是使用抗脉冲疗法进行药物治疗。已经为发生并发症的患者保留了外科手术干预,并且越来越多地以胸腔内血管主动脉修复(TEVAR)的形式进行。与开放式外科手术或药物治疗相比,TEVAR进行急性复杂性夹层的结果非常好,但是TEVAR进行慢性复杂性夹层的结果好坏参半。对于夹层扩张到腹主动脉(最常见的表现)的患者尤其如此。当这些患者接受初次进入泪道的真实内腔的简单TEVAR治疗时,他们仍然容易出现逆行假腔流和主动脉或动脉内脏段远端再入泪道的加压。即使将支架移植物延伸到整个胸主动脉至腹腔动脉水平也是如此。即使在动脉期计算机断层扫描中无法检测到缓慢流动,流入假管腔的回流也会导致持续的破裂风险。在这些患者中,延迟静脉相成像对于检测较慢的逆行血流至关重要,逆行血流可能导致动脉瘤假管腔过度加压。主动脉夹层疾病需要特别复杂的治疗,在慢性期,目前可用的血管内系统不足。

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