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Flexible Ureterorenoscopy for Renal and Proximal Ureteral Stone in Patients with Previous Ureteral Stenting: Impact on Stone-Free Rate and Morbidity

机译:输尿管镜对以前有输尿管支架置入术的患者的肾脏和近端输尿管结石的影响:对无结石率和发病率的影响

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Objective: To analyze results (stone-free rate [SFR]) and complications after flexible ureterorenoscopy (f-URS) for renal or lumbar ureteral lithiasis in patients with a previous ureteral stenting (US). Patients and Methods: We conducted a single-center retrospective study, including all f-URS procedures achieved in our department, between January 2004 and December 2010, for renal or lumbar ureteral urinary lithiasis. In total, 497 procedures were performed: 316 procedures in patients with a ureteral stent placed before the surgery for renal colic, sepsis, or renal failure (group 1) and 181 procedures in patients without US (group 2). Success was defined as a complete SFR at 6-month follow-up. Surgical morbidity was defined using the Clavien-Dindo grading system. Results: Groups 1 and 2 were well balanced in terms of demographic data, number, and size of stones. Ureteral location was significantly higher in group 1 (30.2% vs 16.3%, p=0.0006). Surgery characteristics were similar in both groups. By univariate analysis, SFR tended to be slightly higher in the group with prior ureteral stenting (72% vs 63%, p=0.05). SFR for ureteral location was also higher after previous ureteral stenting (81.5% vs 59.4%, p=0.023). By multivariate analysis, only stone size and number were correlated with f-URS failure. Complication rate was comparable in both groups (10.7% vs 11.8%, p=0.7). Conclusion: Technical aspects of the f-URS procedure were not modified by ureteral stenting. We found that f-URS in patients with ureteral stenting was not associated with a better SFR, except in case of ureteral location in univariate analysis. Ureteral stenting was not independently related to f-URS outcome by multivariate analysis.
机译:目的:分析先前输尿管支架置入术(US)患者的输尿管软镜(f-URS)治疗肾或腰部输尿管结石的结果(无结石率[SFR])和并发症。患者和方法:我们进行了单中心回顾性研究,包括我们部门在2004年1月至2010年12月之间完成的针对肾或腰部输尿管尿路结石的所有f-URS程序。总共进行了497例手术:对于肾绞痛,败血症或肾功能衰竭,在术前放置输尿管支架的患者中进行316例手术(第1组),而在无US的患者中进行181例手术(第2组)。成功定义为在6个月的随访中完成SFR。使用Clavien-Dindo分级系统定义手术发病率。结果:第1组和第2组在人口统计学数据,结石数量和大小方面取得了很好的平衡。第一组的输尿管位置明显更高(30.2%对16.3%,p = 0.0006)。两组的手术特点相似。通过单因素分析,在先前输尿管支架置入组中,SFR倾向于略高(72%vs 63%,p = 0.05)。在先前的输尿管支架置入术后,输尿管位置的SFR也较高(81.5%对59.4%,p = 0.023)。通过多变量分析,只有结石的大小和数量与f-URS失败相关。两组的并发症发生率相当(10.7%vs 11.8%,p = 0.7)。结论:输尿管支架置入术未对f-URS程序的技术方面进行修改。我们发现,输尿管支架置入术患者中的f-URS与更好的SFR无关,除非在单因素分析中将输尿管定位。通过多变量分析,输尿管支架置入术与f-URS结果无关。

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