Enterovirus71 virus-like particles produced from insect cells and purified by multistep chromatography elicit strong humoral immune responses in mice

Zhao D.; Sun B.; Jiang H.; Sun S.; Kong F. T.; Ma Y.; Jiang L.; Bai L.; Chen X.; Yang P.; Liu C.; Xu Y.; Su W.; Kong W.; Xu F.; Jiang C.

首页> 外文期刊>Journal of applied microbiology >Enterovirus71 virus-like particles produced from insect cells and purified by multistep chromatography elicit strong humoral immune responses in mice

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Enterovirus71 virus-like particles produced from insect cells and purified by multistep chromatography elicit strong humoral immune responses in mice

机译：由昆虫细胞产生并经多步色谱纯化的肠病毒71样病毒颗粒在小鼠中引起强烈的体液免疫反应

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Aims: The study aims to develop a novel multistep chromatographic purification process for human enterovirus71 virus-like particles (VLPs) produced from insect cells (Sf9) infected with recombinant baculovirus.

机译：目的：该研究旨在为从重组杆状病毒感染的昆虫细胞（Sf9）产生的人类肠道病毒71病毒样颗粒（VLP）开发一种新颖的多步色谱纯化方法。

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来源
《Journal of applied microbiology》 |2015年第4期|共10页
作者
Zhao D.; Sun B.; Jiang H.; Sun S.; Kong F. T.; Ma Y.; Jiang L.; Bai L.; Chen X.; Yang P.; Liu C.; Xu Y.; Su W.; Kong W.; Xu F.; Jiang C.;
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正文语种 eng
中图分类应用微生物学;
关键词
chromatography; enterovirus 71; immunogenicity; insect cells; virus-like particle;

机译：色谱;肠病毒71;免疫原性;昆虫细胞;病毒样颗粒;

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专利

1. Enterovirus71 virus-like particles produced from insect cells and purified by multistep chromatography elicit strong humoral immune responses in mice [J] . Zhao D., Sun B., Jiang H., Journal of applied microbiology . 2015,第4期

机译：由昆虫细胞产生并经多步色谱纯化的肠病毒71样病毒颗粒在小鼠中引起强烈的体液免疫反应
2. H5N1 influenza virus-like particles produced by transient expression in mammalian cells induce humoral and cellular immune responses in mice [J] . TaoL., ChenJ., ZhengZ., Canadian journal of microbiology . 2012,第4期

机译：在哺乳动物细胞中瞬时表达产生的H5N1流感病毒样颗粒诱导小鼠的体液和细胞免疫反应
3. Porcine epidemic diarrhea virus virus-like particles produced in insect cells induce specific immune responses in mice [J] . Wang Cuiling, Yan Feihu, Zheng Xuexing, Virus Genes . 2017,第4期

机译：野生植物流行性腹泻病毒样颗粒在昆虫细胞中产生诱导小鼠的特定免疫应答
4. IMMUNIZATION WITH FC-BASED RECOMBINANT EPSTEIN-BARR VIRUS GP350 ELICITS POTENT NEUTRALIZING HUMORAL IMMUNE RESPONSE IN A BALB/C MICE MODEL [C] . Bingchun Zhao, Xiao Zhang, Ling Gao, Conference on vaccine technology VI . 2018

机译：基于FC的重组EPSTEIN-BARR病毒GP350的免疫接种可在BALB / C小鼠模型中有效中和人体免疫反应
5. The TH2 bias in CNS immune privilege: Induction of humoral, cellular, and cytokine immune responses to soluble protein antigen administered into the cerebrospinal fluid of mice with normal blood brain barrier permeability. [D] . Park, Joel Thomas, II. 2003

机译：在中枢神经系统免疫特权中的TH2偏倚：诱导对可溶性蛋白抗原的体液，细胞和细胞因子免疫反应，这些抗原被注入具有正常血脑屏障通透性的小鼠的脑脊液中。
6. Porcine epidemic diarrhea virus virus-like particles produced in insect cells induce specific immune responses in mice [O] . Cuiling Wang, Feihu Yan, Xuexing Zheng, -1

机译：昆虫细胞中产生的猪流行性腹泻病毒病毒样颗粒在小鼠中诱导特异性免疫反应
7. Enterovirus71 virus-like particles produced from insect cells and purified by multistep chromatography elicit strong humoral immune responses in mice [O] . D. Zhao, B. Sun, H. Jiang, 2015

机译：肠道病毒71种异常颗粒由昆虫细胞产生，并通过MultiSep色谱纯化，纯化小鼠中的强液体免疫应答

Enterovirus71 virus-like particles produced from insect cells and purified by multistep chromatography elicit strong humoral immune responses in mice

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