Simultaneous topography-guided partial photorefractive keratectomy and corneal collagen crosslinking for keratoconus

摘要

Purpose To report the visual, refractive, and clinical outcomes of simultaneous topography-guided partial photorefractive keratectomy (PRK) and corneal collagen crosslinking (CXL) in eyes with keratoconus. Setting Private practice surgery center, Dubai, United Arab Emirates. Design Retrospective cohort study. Methods Refraction, uncorrected (UDVA) and corrected (CDVA) distance visual acuities, flat and steep keratometry (K) readings, and complications were evaluated 1, 3, 6, and 12 months postoperatively. Results The study enrolled 31 eyes of 31 patients aged 21 to 42 years. All study parameters showed a statistically significant improvement at 3, 6, and 12 months over baseline values. At 12 months, the mean UDVA improved to 0.23 logMAR ± 0.33 (SD) from 0.79 ± 0.36 logMAR (P<.001) and the CDVA improved to 0.06 ± 0.07 logMAR from 0.28 ± 0.20 logMAR (P<.001). The mean defocus decreased from 3.45 ± 1.60 diopters (D) to 1.88 ± 1.58 D (P<.001). The flat K and steep K readings showed significant flattening. The mean refractive astigmatism decreased from -2.77 ± 1.47 D to -0.98 ± 0.76 D (P<.001). The improvement in study parameters plateaued after 3 months. Conclusion Simultaneous topography-guided partial PRK and CXL was effective, safe, and stable in keratoconus patients. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.