Combined collagen crosslinking treatments for keratoconus

摘要

The landscape of keratoconus treatment has changed profoundly since the introduction of corneal collagen crosslinking (CXL). A decade ago, a newly diagnosed keratoconus patient could expect a treatment plan that involved gradual escalation from spectacle correction to contact lens wear, perhaps followed by an attempt to improve contact lens tolerance or spectacle acuity with intrastromal corneal ring segments (ICRS) and then, for some patients, keratoplasty. This path is beset with frustrations for patients and clinicians alike.