Software News and Update Diffusion-Collision Model Algorithms for Protein Folding Kinetics

摘要

The diffusion-collision model (DCM) of protein folding is described qualitatively and quantitatively.The input parameters required to perform a calculation are explained,and the output data are outlined.Three examples are given of calculating DCM folding kinetics: the Engrailed Homeodomain (a three-helix bundle with three helical microdomains,pdb code 1ENH),protein G (with three microdomains having a beta-hairpin-o;-helix-beta-hairpin motif,pdb code 1PGA),and apomyoglobin (with eight helices and seven strong microdomain-microdomain pairings).