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Influence of an interpositional spacer on the behaviour of the tibiofemoral joint: a finite element study.

机译:介入间隔物对胫股关节行为的影响:有限元研究。

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BACKGROUND: Interpositional arthroplasty is considered by many surgeons for the treatment of isolated medial compartment osteoarthritis of the knee. In this procedure, an interpositional spacer is inserted into the medial compartment of the joint with no bone resection and no mechanical fixation. Major problems such as implant dislocation, severe pain or need for revision have been reported post-operatively. METHODS: In this study, the kinematics of a knee implanted with an interpositional spacer made of either polyurethane or cobalt-chrome during walking, stair ascent and squatting cycles have been predicted and compared to the normal knee using finite element analysis. In addition, articular cartilage stress histories have been examined to obtain distributions of cumulative stress, a measure of the likelihood of articular cartilage degeneration. FINDINGS: The insertion of a polyurethane interpositional spacer in the medial side of the knee did not affect knee kinematics as compared to the normal knee, but caused an increase of articular cartilage cumulative contact stress exposures in the medial compartment of the joint. The knee implanted with the Co-Cr spacer exhibited similar trends in knee kinematics, however significantly different ranges of motion were observed during some periods of the activity cycles, specifically during the first half of the walking cycle where lower ranges of motion were predicted. In addition, higher articular cartilage cumulative contact stress exposures were observed in both compartments of the knee. In both cases, cumulative contact stress exposures of the tibial articular cartilage were more affected than those of the femoral articular cartilage. INTERPRETATION: These results suggest implant material as an important parameter in the design phase of interpositional spacers.
机译:背景:许多外科医生考虑进行间质性关节置换术,以治疗孤立的膝关节内侧腔室骨关节炎。在此过程中,将中间间隔物插入关节的中间腔室,而无需进行骨切除和机械固定。术后已报告了诸如植入物脱位,严重疼痛或需要翻修等主要问题。方法:在这项研究中,已经预测了在步行,楼梯上升和蹲下过程中植入由聚氨酯或钴铬合金制成的中间垫片的膝盖的运动学,并通过有限元分析将其与正常膝盖进行了比较。此外,已经检查了关节软骨应力的历史,以获得累积应力的分布,这是对关节软骨退化可能性的一种度量。结果:与正常膝关节相比,在聚氨酯膝关节内侧插入聚氨酯插入垫片不会影响膝关节运动学,但会增加关节内侧关节软骨累积的接触应力暴露。植入了Co-Cr垫片的膝盖在膝关节运动学方面表现出相似的趋势,但是在活动周期的某些时间段内观察到明显不同的运动范围,特别是在步行周期的前半段(预测到较低的运动范围)。另外,在膝盖的两个隔间中都观察到较高的关节软骨累积接触应力暴露。在这两种情况下,胫骨软骨的累积接触应力暴露均比股骨软骨受到更大的影响。解释:这些结果表明植入材料是插入间隔物设计阶段的重要参数。

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