Comparison of the Liaison (R) Calprotectin kit with a well established point of care test (Quantum Blue - Buhlmann-Alere (R)) in terms of analytical performances and ability to detect relapses amongst a Crohn population in follow-up

摘要

Background: Although colonoscopy associated with histopathological sampling remains the gold standard in the diagnostic and follow-up of inflammatory bowel disease (IBD), calprotectin is becoming an essential biomarker in gastroenterology. The aim of this work is to compare a newly developed kit (Liaison (R) Calprotectin-Diasorin (R)) and its two distinct extraction protocols (weighing and extraction device protocol) with a well established point of care test (Quantum Blue (R) - Buhlmann-Alere (R)) in terms of analytical performances and ability to detect relapses amongst a Crohn's population in follow-up.