Synthesis of tetrasubstituted olefins by stereoselective allylzincation–Negishi tandem reaction of acetylenic sulfones

摘要

Tetrasubstituted olefins containing a 1,3,6-triene structural unit can be regio- and stereoselectively synthesised in good yields under mild conditions in one pot, by allylzincation–Negishi tandem reaction of acetylenic sulfones with allylzinc bromide and alkenyl halides.