Solubility of Captopril in 2-Propanol, Acetone, Acetonitrile, Methyl Acetate, Ethyl Acetate, and Butyl Acetate

摘要

The solubility of captopril in 2-propanol, acetone, acetonitrile, methyl acetate, ethyl acetate, and butyl acetate was measured by a synthetic method over the temperature range of (278.15 to 313.15) K at atmosphere pressure. The results show that the solubility of captopril increases with increasing temperature. The experimental data were correlated with the van't Hoff equation, and the agreement was very good.