European Best Practice Guidelines for Quality Assurance, Provision and Use of Genome-based Information and Technologies: the 2012 Declaration of Rome.

摘要

Genomics is a highly dynamic field and, as such, represents a moving target for public health. Public health is shifting from a focus on the population towards an emphasis of the individual as a means of supporting the wellbeing of the population. In particular, we are entering the era of predictive, personalised, preemptive and participatory (P4) medicine supported by advanced technological infrastructure. These changes represent a paradigm shift in our approach to healthcare and will go hand-in-hand with a major reclassification of diseases. The challenge now is to understand how all of these changes will impact public health and how to ensure that they are translated effectively into benefits for individual citizens and society as a whole. Thus, there is a need to develop guidelines aiming not to close doors. Instead, the goal is to create a vision that allows for flexibility and adaptability in their implementation in order to have a maximum impact on health, the healthcare infrastructure, health technologies and economic growth in the health sector.