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首页> 外文期刊>Journal of assisted reproduction and genetics >Association between a PD-1 gene polymorphism and antisperm antibody-related infertility in Iranian men
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Association between a PD-1 gene polymorphism and antisperm antibody-related infertility in Iranian men

机译:PD-1基因多态性与伊朗男性抗精子抗体相关的不育之间的关系

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摘要

Programmed cell death-1 (PD-1, Pdcd1), an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signalling by recruiting protein tyrosine phosphatase, SHP-2 upon interacting with either of two ligands, PD-L1 or PD-L2. This study investigates PD-1 gene polymorphism in patients with antisperm antibody-related infertility
机译:程序性细胞死亡1(PD-1,Pdcd1)是CD28 / CTLA-4家族的一种免疫受体,与两种配体PD-L1或L-L1或L-L1或L-L1或L-L1或L-L1两种配体相互作用后,通过募集蛋白酪氨酸磷酸酶SHP-2负调节抗原受体信号传导。 PD-L2。这项研究调查了抗精子抗体相关性不育患者的PD-1基因多态性

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