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Selection and Interpretation of Diagnostic Tests in Aquaculture Biosecurity

机译:水产养殖生物安全性诊断测试的选择和解释

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In biosecurity-related activities in aquaculture, diagnostic tests are commonly used to (1) demonstrate freedom from infection in a facility, (2) screen aquatic animals prior to introduction to the receiving facility, (3) detect infected animals as early as possible during a quarantine period, and (4) confirm suspicious or clinical case(s). The interpretation of test result(s) is indicative of the true infection status at the individual and at the group levels and has direct implications in completing the stepwise process for Effective Veterinary Biosecurity as proposed by the International Aquatic Veterinary Biosecurity Consortium. The confidence regarding a test result depends on the anticipated level of infection in the investigated aquatic animal population and on the diagnostic sensitivity and specificity of the tests. Depending on the testing intended purpose, the test of choice or combination of test may vary and is primarily based on the test diagnostic sensitivity or specificity. Additional strategies for maximizing the chance of a test result to be true are described in the context of each testing activity and targeted unit of interest (i.e., individual fish or group of fish).
机译:在水产养殖中与生物安全有关的活动中,诊断测试通常用于(1)证明设施内不受感染;(2)在引入接收设施之前对水生动物进行筛查;(3)在感染期间尽可能早地检测到被感染的动物隔离期,以及(4)确认可疑或临床病例。测试结果的解释说明了个人和团体的真实感染状况,并且对完成国际水生兽医生物安全联盟提出的有效兽医生物安全逐步过程具有直接影响。对检测结果的置信度取决于所调查的水生动物种群中预期的感染水平以及检测的诊断敏感性和特异性。根据测试的预期目的,选择的测试或测试的组合可能会有所不同,并且主要基于测试的诊断敏感性或特异性。在每种测试活动和目标感兴趣的目标单元(即个别鱼或鱼群)的背景下,介绍了使测试结果为真的机会最大化的其他策略。

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