In reply: Superior recovery profiles of propofol-based regimen as compared to isoflurane-based regimen in patients undergoing craniotomy for primary brain tumor excision: A retrospective study

摘要

To the Editor: Firstly, we are aware that the extubation time was prolonged in our results [1] compared with those in modern neuroanesthesia practice. A recent RCT study reported 8-10 min emergence time in postoperative patients of elective supratentorial craniotomy anesthetized by sevo-flurane-remifentanil or by propofol-remifentanil anesthesia [2]. The emergence was, however, delayed during the period of investigation. The author had discussed the differences of anesthesia emergence profiles in the past and current conditions with the co-authors and recognized that the presented cases of Yamagata University Hospital 2002-2005 were suitable to be provided for re-examination on the effects of isoflurane and propofol in relation to the reasons specified in the paper. In addition to the above, it should be noted that neurosurgical procedures have been much improved since the time we conducted that research. Remarkable advancement of imaging technology and the development of surgical instruments have enabled the surgeon to perform less invasive surgery, of higher quality and shorter surgical duration.