Diet and prevention of Alzheimer disease.

摘要

ALZHEIMER DISEASE (AD) IS ONE OF THE MOST IMPOR-tant public health problems of the 21st century. Currently, 5.3 million US individuals have AD but the number is expected to increase by 300% over the next 40 years as the oldest age categories make up an increasingly large percentage of the population.1 However, to date, there is no cure for the disease and no effective therapeutic interventions. In 2010, the estimated US annual expenditure is approximately Dollars 172 billion for persons with AD and other dementias for all health care and long-term care services.2 Thus, the social and economic toll of AD on society is substantial, making preventive strategies all the more important.